Strep B Test Card
- Article ID
- ulti med Products (Deutschland) GmbH
- Handling time
The ulti med Streptococcus B Cassette is a rapid chromatographic immunoassay for the qualitative detection of Strep B antigen in samples taken from vaginal, rectal swabs of pregnant women or diverse swabs from newborn. This kit is intended for use as an aid in the diagnosis of Strep B infection.
Group B Streptococci (GBS) or Streptococcus agalactiae are among the most frequent causes of life-threatening infectious in neonates. Between 5% and 30% of all pregnant women are colonized with GBS.1 Several recent studies have shown that the intrapartum treatment of GBS-colonized women significantly reduces the incidence of GBS-caused sepsis. Therefore, screening for GBS is important and the US American authorities (Center for Disease Control and Prevention, CDC) emphasize the routine examination for the Group B streptococcus between the 35th and the 37th week of pregnancy. A CDC study results that routine examinations is 50% more effective than the use of antibiotics for pregnant women with clinical risk factors. Standard culture methods require 24 to 48 hours, and the results may not be available soon enough for efficient treatment. Thus, methods utilizing more rapid screening techniques are required.
The ulti med Streptococcus B Cassette detects Group B Streptococcus antigens through visual interpretation of color development on the internal strip. Anti-Strep B antibodies are immobilized on the test region of the membrane. During the test, the specimen reacts with polyclonal anti-Strep B antibodies conjugated to colored particles and precoated onto the sample pad of the test. The mixture then migrates through the membrane by capillary action and interacts with reagents on the membrane. If there is sufficient Strep B antigen in the specimen, a colored band will form at the test region of the membrane. The presence of this colored band indicates a positive result, while its absence indicates a negative result. The appearance of a colored band at the control region serves as a procedural control, indicating that proper volume of specimen has been added and membrane wicking has occurred.